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Case-control study.

Compares affected and unaffected individuals retrospectively. Useful for rare events, sensitive to recall error.

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HUHuman

Carbon-14 bomb pulse dating shows that tendinopathy is preceded by years of abnormally high collagen turnover

2018 · FASEB Journal

In 25 tendinopathic versus 10 healthy Achilles tendons, a substantial share of the collagen had been renewed in adulthood; the modelling points to years of raised turnover before symptom onset.

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HOHorse

Case control study to identify risk factors for simple colonic obstruction and distension colic in horses

2002 · Equine Veterinary Journal

Crib-biting, increasing hours stabled, a recent change to the exercise programme, no ivermectin or moxidectin treatment in the previous year and transport in the last 24 hours were associated with simple colonic obstruction, most strongly permanent stabling, crib-biting and transport.

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HOHorse

Risk factors for epiploic foramen entrapment colic: an international study

2008 · Equine Veterinary Journal

Among 109 cases and 310 comparison horses, crib-biting was by far the strongest factor for entrapment in the epiploic foramen, followed by a colic in the previous year and greater height, although the estimates carry wide ranges of uncertainty.

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HOHorse

Risk factors for epiploic foramen entrapment colic in a UK horse population: a prospective case-control study

2008 · Equine Veterinary Journal

The British parallel study with 77 cases and 216 comparison horses confirmed crib-biting as the strongest factor and additionally found a colic in the previous year, more time stabled in the preceding 28 days and greater height to raise the risk.

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HOHorse

Risk factors for equine strangulating lipoma colic: An international, case-control study

2025 · Equine Veterinary Journal

Among 55 cases and 167 comparison horses, age, certain breeds, a previous bout of laminitis and more time stabled in the four weeks beforehand raised the risk of strangulation by a pedunculated lipoma, while weight management went with it less often.

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HOHorse

The association between Anoplocephala perfoliata and colic in Swedish horses: a case control study

2013 · Veterinary Parasitology

With 67 horses in each group, detection of tapeworm eggs in the droppings went with an around sixteen-fold higher odds of colic, while no association could be shown using antibody testing in blood.

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HOHorse

Comparative Analysis of Intestinal Helminth Infections in Colic and Non-Colic Control Equine Patients

2020 · Animals

In 620 mostly adult hospital horses there was no relationship between tapeworm or large strongyle antibodies and colic status; horses wormed in the preceding week did, however, have an around 2.4-fold higher odds of colic signs than horses treated at least eight weeks earlier.

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HOHorse

Factors associated with development of ileal impaction in horses with surgical colic: 78 cases (1986-2000)

2002 · Equine Veterinary Journal

In 78 surgically confirmed ileal impactions against 100 other colic cases, feeding coastal Bermuda hay and the absence of pyrantel treatment within three months were each associated with an around three-fold raised risk.

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